Protecting the heart

Protecting the Heart From Lipid Overload

In this review, we attempt to deduce teleologically the physiological mission of leptin. Because overnutrition and diet-induced obesity are the only known causes of hyperleptinemia, we contrast the differences in overnutrition in normally leptinized rodents, in which the added lipids are confined to adipocytes, with those of unleptinized rodents, in which the added lipids are distributed in liv...

Hyperleptinemia: protecting the heart from lipid overload.

In this review, we attempt to deduce teleologically the physiological mission of leptin. Because overnutrition and diet-induced obesity are the only known causes of hyperleptinemia, we contrast the differences in overnutrition in normally leptinized rodents, in which the added lipids are confined to adipocytes, with those of unleptinized rodents, in which the added lipids are distributed in liv...

Safety first: protecting the heart, then the head.

Protecting the clean athlete, protecting health

The vision of the IOC is to change the world for the better through sport and to promote social change. Protecting the health of the athlete is an important part of this vision, in order to protect the integrity of sport, protect elite athletes, protect the health of all those exercising and to promote physical activity. The protection of clean athletes through doping control is also important ...

Protecting the myocardium: a role for the beta2 adrenergic receptor in the heart.

OBJECTIVE The sympathetic nervous system enhances cardiac muscle function by activating beta adrenergic receptors (betaARs). Recent studies suggest that chronic betaAR stimulation is detrimental, however, and that it may play a role in the clinical deterioration of patients with congestive heart failure. To examine the impact of chronic beta1AR and beta2AR subtype stimulation individually, we s...